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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNB1 All Species: 41.21
Human Site: Y404 Identified Species: 75.56
UniProt: P14635 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14635 NP_114172.1 433 48337 Y404 H M T V K N K Y A T S K H A K
Chimpanzee Pan troglodytes XP_517728 536 59103 Y507 H M T V K N K Y A T S K H A K
Rhesus Macaque Macaca mulatta XP_001091533 433 48375 Y404 H M T V K N K Y A T S K H A K
Dog Lupus familis XP_850398 425 47378 Y396 H M T I K N K Y A A S K H A K
Cat Felis silvestris
Mouse Mus musculus P24860 430 48033 Y401 H M T V K N K Y A A S K H A K
Rat Rattus norvegicus P30277 423 47373 Y394 H M T I K N K Y A T S K H A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507609 428 47366 Y399 H V T I K N K Y A S S K H A R
Chicken Gallus gallus P29332 399 44633 Y372 Y T A V R N K Y A S S K L L R
Frog Xenopus laevis P13350 397 44655 Y370 H L T V K N K Y A S S K Q M K
Zebra Danio Brachydanio rerio NP_571588 398 44818 Y371 H L A V K N K Y S S Q K Q M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20439 530 59237 Y501 L K A I Y N K Y Q G S K F Q K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39071 444 50417 Y421 L I A I H T K Y N Q Q K F K R
Baker's Yeast Sacchar. cerevisiae P24869 491 56228 K467 Y Q S R R F M K A S I I S V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.5 98.6 91.2 N.A. 86.3 84.7 N.A. 75.7 50.5 66.2 61.8 N.A. 34.3 N.A. N.A. N.A.
Protein Similarity: 100 80.5 99.3 94 N.A. 91.9 90.5 N.A. 84.5 66.9 78.2 75.7 N.A. 49.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 73.3 46.6 73.3 46.6 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 100 N.A. 100 73.3 86.6 73.3 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.4 30.3 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 31 0 0 0 0 0 77 16 0 0 0 54 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 16 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 70 0 0 0 8 0 0 0 0 0 0 0 54 0 0 % H
% Ile: 0 8 0 39 0 0 0 0 0 0 8 8 0 0 0 % I
% Lys: 0 8 0 0 70 0 93 8 0 0 0 93 0 8 62 % K
% Leu: 16 16 0 0 0 0 0 0 0 0 0 0 8 8 0 % L
% Met: 0 47 0 0 0 0 8 0 0 0 0 0 0 16 0 % M
% Asn: 0 0 0 0 0 85 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 8 8 16 0 16 8 8 % Q
% Arg: 0 0 0 8 16 0 0 0 0 0 0 0 0 0 31 % R
% Ser: 0 0 8 0 0 0 0 0 8 39 77 0 8 0 0 % S
% Thr: 0 8 62 0 0 8 0 0 0 31 0 0 0 0 0 % T
% Val: 0 8 0 54 0 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 8 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _